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While recent zero-shot multispeaker text-to-speech (TTS) models achieve impressive results, they typically rely on extensive transcribed speech datasets from numerous speakers and intricate training pipelines. Meanwhile, self-supervised learning (SSL) speech features have emerged as effective intermediate representations for TTS. It was also observed that SSL features from different speakers that are linearly close share phonetic information while maintaining individual speaker identity, which enables straight-forward and robust voice cloning. In this study, we introduce SSL-TTS, a lightweight and efficient zero-shot TTS framework trained on transcribed speech from a single speaker. SSL-TTS leverages SSL features and retrieval methods for simple and robust zero-shot multi-speaker synthesis. Objective and subjective evaluations show that our approach achieves performance comparable to state-of-the-art models that require significantly larger training datasets. The low training data requirements mean that SSL-TTS is well suited for the development of multi-speaker TTS systems for low-resource domains and languages. We also introduce an interpolation parameter which enables fine control over the output speech by blending voices. Demo samples are available at https://idiap.github.io/ssl-tts

Generating physician letters is a time-consuming task in daily clinical practice. This study investigates local fine-tuning of large language models (LLMs), specifically LLaMA models, for physician letter generation in a privacy-preserving manner within the field of radiation oncology. Our findings demonstrate that base LLaMA models, without fine-tuning, are inadequate for effectively generating physician letters. The QLoRA algorithm provides an efficient method for local intra-institutional fine-tuning of LLMs with limited computational resources (i.e., a single 48 GB GPU workstation within the hospital). The fine-tuned LLM successfully learns radiation oncology-specific information and generates physician letters in an institution-specific style. ROUGE scores of the generated summary reports highlight the superiority of the 8B LLaMA-3 model over the 13B LLaMA-2 model. Further multidimensional physician evaluations of 10 cases reveal that, although the fine-tuned LLaMA-3 model has limited capacity to generate content beyond the provided input data, it successfully generates salutations, diagnoses and treatment histories, recommendations for further treatment, and planned schedules. Overall, clinical benefit was rated highly by the clinical experts (average score of 3.44 on a 4-point scale). With careful physician review and correction, automated LLM-based physician letter generation has significant practical value.

This study addresses the interaction challenges encountered by spoken dialogue systems (SDSs) when engaging with users who exhibit distinct conversational behaviors, particularly minors, in scenarios where data are scarce. We propose a novel data augmentation framework to enhance SDS performance for user groups with limited resources. Our approach leverages a large language model (LLM) to extract speaker styles and a pre-trained language model (PLM) to simulate dialogue act history. This method generates enriched and personalized dialogue data, facilitating improved interactions with unique user demographics. Extensive experiments validate the efficacy of our methodology, highlighting its potential to foster the development of more adaptive and inclusive dialogue systems.

While large language models (LLMs) have been thoroughly evaluated for deductive and inductive reasoning, their proficiency in abductive reasoning and holistic rule learning in interactive environments remains less explored. We introduce RULEARN, a novel benchmark specifically designed to assess the rule-learning abilities of LLM agents in interactive settings. In RULEARN, agents strategically interact with simulated environments to gather observations, discern patterns, and solve complex problems. To enhance the rule-learning capabilities for LLM agents, we propose IDEA, a novel reasoning framework that integrates the process of Induction, Deduction, and Abduction. The IDEA agent generates initial hypotheses from limited observations through abduction, devises plans to validate these hypotheses or leverages them to solve problems via deduction, and refines previous hypotheses using patterns identified from new observations through induction, dynamically establishing and applying rules that mimic human rule-learning behaviors. Our evaluation of the IDEA framework, which involves five representative LLMs, demonstrates significant improvements over the baseline. Furthermore, within this framework, our comparison with 50 human participants reveals notable discrepancies in rule-learning behaviors. LLM agents tend to generate plausible initial hypotheses but struggle to refine them through interaction. Conversely, humans, despite sometimes overlooking initial details, excel at incorporating feedback and continuously improving their hypotheses. We believe our benchmark, RULEARN, will serve as a valuable and challenging resource, and that the IDEA framework will provide crucial insights for the development of LLM agents capable of human-like rule learning in real-world scenarios. We will release our code and data upon acceptance of the paper.

Mixture of Experts (MoE) offers remarkable performance and computational efficiency by selectively activating subsets of model parameters. Traditionally, MoE models use homogeneous experts, each with identical capacity. However, varying complexity in input data necessitates experts with diverse capabilities, while homogeneous MoE hinders effective expert specialization and efficient parameter utilization. In this study, we propose a novel Heterogeneous Mixture of Experts (HMoE), where experts differ in size and thus possess diverse capacities. This heterogeneity allows for more specialized experts to handle varying token complexities more effectively. To address the imbalance in expert activation, we propose a novel training objective that encourages the frequent activation of smaller experts, enhancing computational efficiency and parameter utilization. Extensive experiments demonstrate that HMoE achieves lower loss with fewer activated parameters and outperforms conventional homogeneous MoE models on various pre-training evaluation benchmarks. Codes will be released upon acceptance.

New medical treatment development requires multiple phases of clinical trials. Despite the significant human and financial costs of bringing a drug to market, less than 20% of drugs in testing will make it from the first phase to final approval. Recent literature indicates that the design of the trial protocols significantly contributes to trial performance. We investigated Clinical Trial Outcome Prediction (CTOP) using trial design documents to predict phase transitions automatically. We propose CTP-LLM, the first Large Language Model (LLM) based model for CTOP. We also introduce the PhaseTransition (PT) Dataset; which labels trials based on their progression through the regulatory process and serves as a benchmark for CTOP evaluation. Our fine-tuned GPT-3.5-based model (CTP-LLM) predicts clinical trial phase transition by analyzing the trial's original protocol texts without requiring human-selected features. CTP-LLM achieves a 67% accuracy rate in predicting trial phase transitions across all phases and a 75% accuracy rate specifically in predicting the transition from Phase~III to final approval. Our experimental performance highlights the potential of LLM-powered applications in forecasting clinical trial outcomes and assessing trial design.

Large Language Model (LLM)-based generative recommendation has achieved notable success, yet its practical deployment is costly particularly due to excessive inference latency caused by autoregressive decoding. For lossless LLM decoding acceleration, Speculative Decoding (SD) has emerged as a promising solution. However, applying SD to generative recommendation presents unique challenges due to the requirement of generating top-K items (i.e., K distinct token sequences) as a recommendation list by beam search. This leads to more stringent verification in SD, where all the top-K sequences from the target LLM must be successfully drafted by the draft model at each decoding step. To alleviate this, we consider 1) boosting top-K sequence alignment between the draft model and the target LLM, and 2) relaxing the verification strategy to reduce trivial LLM calls. To this end, we propose an alignment framework named AtSpeed, which presents the AtSpeed-S optimization objective for top-K alignment under the strict top-K verification. Moreover, we introduce a relaxed sampling verification strategy that allows high-probability non-top-K drafted sequences to be accepted, significantly reducing LLM calls. Correspondingly, we propose AtSpeed-R for top-K alignment under this relaxed sampling verification. Empirical results on two real-world datasets demonstrate that AtSpeed significantly accelerates LLM-based generative recommendation, e.g., near 2x speedup under strict top-K verification and up to 2.5 speedup under relaxed sampling verification. The codes and datasets will be released in the near future.

Efficient long-context language modeling remains a significant challenge in Natural Language Processing (NLP). While Transformers dominate language tasks, they struggle with long sequences due to quadratic computational complexity in training and linearly scaling memory costs during inference. Recent State Space Models (SSMs) such as Mamba offer alternatives with constant memory usage, but they underperform in tasks requiring extensive in-context retrieval. We introduce Taipan, a novel hybrid architecture that combines Mamba-2 with Selective Attention Layers (SALs). These SALs identify tokens requiring long-range interactions, remove less important features, and then augment their representations using the attention module. This approach balances Mamba's efficiency with Transformer-like performance in memory-intensive tasks. By constraining the attention budget, Taipan extends accurate predictions to context lengths of up to 1 million tokens while preserving computational efficiency. Our experiments demonstrate Taipan's superior performance across various scales and tasks, offering a promising solution for efficient long-context language modeling.

With significant efforts in recent studies, LLM-as-a-Judge has become a cost-effective alternative to human evaluation for assessing the text generation quality in a wide range of tasks. However, there still remains a reliability gap between LLM-as-a-Judge and human evaluation. One important reason is the lack of guided oracles in the evaluation process. Motivated by the role of reference pervasively used in classic text evaluation, we introduce RevisEval, a novel text generation evaluation paradigm via the response-adapted references. RevisEval is driven by the key observation that an ideal reference should maintain the necessary relevance to the response to be evaluated. Specifically, RevisEval leverages the text revision capabilities of large language models (LLMs) to adaptively revise the response, then treat the revised text as the reference (response-adapted reference) for the subsequent evaluation. Extensive experiments demonstrate that RevisEval outperforms traditional reference-free and reference-based evaluation paradigms that use LLM-as-a-Judge across NLG tasks and open-ended instruction-following tasks. More importantly, our response-adapted references can further boost the classical text metrics, e.g., BLEU and BERTScore, compared to traditional references and even rival the LLM-as-a-Judge. A detailed analysis is also conducted to confirm RevisEval's effectiveness in bias reduction, the impact of inference cost, and reference relevance.

This paper investigates controllable generation for large language models (LLMs) with prompt-based control, focusing on Lexically Constrained Generation (LCG). We systematically evaluate the performance of LLMs on satisfying lexical constraints with prompt-based control, as well as their efficacy in downstream applications. We conclude that LLMs face significant challenges in consistently satisfying lexical constraints with prompt-based control. We identified three key limitations of LLMs for LCG, including (1) position bias, where LLMs tend to satisfy constraints that appear in specific positions within the input; (2) low responsiveness to decoding parameters, which render minimal impact on control of LLMs; and (3) struggle with handling the inherent complexity of certain constraints (e.g., compound words). To address these issues, we introduce a Divide and Conquer Generation strategy, effective for both white-box and black-box LLMs, to enhance LLMs performance in LCG tasks, which demonstrates over 90% improvement on success rate in the most challenging LCG task. Our analysis provides valuable insights into the performance of LLMs in LCG with prompt-based control, and our proposed strategy offers a pathway to more sophisticated and customized text generation applications.

Large Language Models (LLMs) have become pervasive due to their knowledge absorption and text-generation capabilities. Concurrently, the copyright issue for pretraining datasets has been a pressing concern, particularly when generation includes specific styles. Previous methods either focus on the defense of identical copyrighted outputs or find interpretability by individual tokens with computational burdens. However, the gap between them exists, where direct assessments of how dataset contributions impact LLM outputs are missing. Once the model providers ensure copyright protection for data holders, a more mature LLM community can be established. To address these limitations, we introduce CopyLens, a new framework to analyze how copyrighted datasets may influence LLM responses. Specifically, a two-stage approach is employed: First, based on the uniqueness of pretraining data in the embedding space, token representations are initially fused for potential copyrighted texts, followed by a lightweight LSTM-based network to analyze dataset contributions. With such a prior, a contrastive-learning-based non-copyright OOD detector is designed. Our framework can dynamically face different situations and bridge the gap between current copyright detection methods. Experiments show that CopyLens improves efficiency and accuracy by 15.2% over our proposed baseline, 58.7% over prompt engineering methods, and 0.21 AUC over OOD detection baselines.

Visual text design plays a critical role in conveying themes, emotions, and atmospheres in multimodal formats such as film posters and album covers. Translating these visual and textual elements across languages extends the concept of translation beyond mere text, requiring the adaptation of aesthetic and stylistic features. To address this, we introduce a novel task of Multimodal Style Translation (MuST-Bench), a benchmark designed to evaluate the ability of visual text generation models to perform translation across different writing systems while preserving design intent. Our initial experiments on MuST-Bench reveal that existing visual text generation models struggle with the proposed task due to the inadequacy of textual descriptions in conveying visual design. In response, we introduce SIGIL, a framework for multimodal style translation that eliminates the need for style descriptions. SIGIL enhances image generation models through three innovations: glyph latent for multilingual settings, pretrained VAEs for stable style guidance, and an OCR model with reinforcement learning feedback for optimizing readable character generation. SIGIL outperforms existing baselines by achieving superior style consistency and legibility while maintaining visual fidelity, setting itself apart from traditional description-based approaches. We release MuST-Bench publicly for broader use and exploration https://huggingface.co/datasets/yejinc/MuST-Bench.