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Evidence to guide healthcare decisions is often limited by a lack of relevant and trustworthy literature as well as difficulty in contextualizing existing research for a specific patient. Large language models (LLMs) could potentially address both challenges by either summarizing published literature or generating new studies based on real-world data (RWD). We evaluated the ability of five LLM-based systems in answering 50 clinical questions and had nine independent physicians review the responses for relevance, reliability, and actionability. As it stands, general-purpose LLMs (ChatGPT-4, Claude 3 Opus, Gemini Pro 1.5) rarely produced answers that were deemed relevant and evidence-based (2% - 10%). In contrast, retrieval augmented generation (RAG)-based and agentic LLM systems produced relevant and evidence-based answers for 24% (OpenEvidence) to 58% (ChatRWD) of questions. Only the agentic ChatRWD was able to answer novel questions compared to other LLMs (65% vs. 0-9%). These results suggest that while general-purpose LLMs should not be used as-is, a purpose-built system for evidence summarization based on RAG and one for generating novel evidence working synergistically would improve availability of pertinent evidence for patient care.
Representation of systems using the SAPPhIRE model of causality can be an inspirational stimulus in design. However, creating a SAPPhIRE model of a technical or a natural system requires sourcing technical knowledge from multiple technical documents regarding how the system works. This research investigates how to generate technical content accurately relevant to the SAPPhIRE model of causality using a Large Language Model, also called LLM. This paper, which is the first part of the two-part research, presents a method for hallucination suppression using Retrieval Augmented Generating with LLM to generate technical content supported by the scientific information relevant to a SAPPhIRE con-struct. The result from this research shows that the selection of reference knowledge used in providing context to the LLM for generating the technical content is very important. The outcome of this research is used to build a software support tool to generate the SAPPhIRE model of a given technical system.
Large language model (LLM)-based applications consist of both LLM and non-LLM components, each contributing to the end-to-end latency. Despite great efforts to optimize LLM inference, end-to-end workflow optimization has been overlooked. Existing frameworks employ coarse-grained orchestration with task modules, which confines optimizations to within each module and yields suboptimal scheduling decisions. We propose fine-grained end-to-end orchestration, which utilizes task primitives as the basic units and represents each query's workflow as a primitive-level dataflow graph. This explicitly exposes a much larger design space, enables optimizations in parallelization and pipelining across primitives of different modules, and enhances scheduling to improve application-level performance. We build Teola, a novel orchestration framework for LLM-based applications that implements this scheme. Comprehensive experiments show that Teola can achieve up to 2.09x speedup over existing systems across various popular LLM applications.
Despite the growing importance of Arabic as a global language, there is a notable lack of language models pre-trained exclusively on Arabic data. This shortage has led to limited benchmarks available for assessing language model performance in Arabic. To address this gap, we introduce two novel benchmarks designed to evaluate models' mathematical reasoning and language understanding abilities in Arabic. These benchmarks are derived from a General Aptitude Test (GAT) called Qiyas exam, a standardized test widely used for university admissions in Saudi Arabia. For validation purposes, we assess the performance of ChatGPT-3.5-trubo and ChatGPT-4 on our benchmarks. Our findings reveal that these benchmarks pose a significant challenge, with ChatGPT-4 achieving an overall average accuracy of 64%, while ChatGPT-3.5-trubo achieved an overall accuracy of 49% across the various question types in the Qiyas benchmark. We believe the release of these benchmarks will pave the way for enhancing the mathematical reasoning and language understanding capabilities of future models tailored for the low-resource Arabic language.
In industrial countries, adults spend a considerable amount of time sedentary each day at work, driving and during activities of daily living. Characterizing the seated upper body human poses using mmWave radars is an important, yet under-studied topic with many applications in human-machine interaction, transportation and road safety. In this work, we devise SUPER, a framework for seated upper body human pose estimation that utilizes dual-mmWave radars in close proximity. A novel masking algorithm is proposed to coherently fuse data from the radars to generate intensity and Doppler point clouds with complementary information for high-motion but small radar cross section areas (e.g., upper extremities) and low-motion but large RCS areas (e.g. torso). A lightweight neural network extracts both global and local features of upper body and output pose parameters for the Skinned Multi-Person Linear (SMPL) model. Extensive leave-one-subject-out experiments on various motion sequences from multiple subjects show that SUPER outperforms a state-of-the-art baseline method by 30 -- 184%. We also demonstrate its utility in a simple downstream task for hand-object interaction.
We present MST-MIXER - a novel video dialog model operating over a generic multi-modal state tracking scheme. Current models that claim to perform multi-modal state tracking fall short of two major aspects: (1) They either track only one modality (mostly the visual input) or (2) they target synthetic datasets that do not reflect the complexity of real-world in the wild scenarios. Our model addresses these two limitations in an attempt to close this crucial research gap. Specifically, MST-MIXER first tracks the most important constituents of each input modality. Then, it predicts the missing underlying structure of the selected constituents of each modality by learning local latent graphs using a novel multi-modal graph structure learning method. Subsequently, the learned local graphs and features are parsed together to form a global graph operating on the mix of all modalities which further refines its structure and node embeddings. Finally, the fine-grained graph node features are used to enhance the hidden states of the backbone Vision-Language Model (VLM). MST-MIXER achieves new state-of-the-art results on five challenging benchmarks.
Disentanglement of visual features of primitives (i.e., attributes and objects) has shown exceptional results in Compositional Zero-shot Learning (CZSL). However, due to the feature divergence of an attribute (resp. object) when combined with different objects (resp. attributes), it is challenging to learn disentangled primitive features that are general across different compositions. To this end, we propose the solution of cross-composition feature disentanglement, which takes multiple primitive-sharing compositions as inputs and constrains the disentangled primitive features to be general across these compositions. More specifically, we leverage a compositional graph to define the overall primitive-sharing relationships between compositions, and build a task-specific architecture upon the recently successful large pre-trained vision-language model (VLM) CLIP, with dual cross-composition disentangling adapters (called L-Adapter and V-Adapter) inserted into CLIP's frozen text and image encoders, respectively. Evaluation on three popular CZSL benchmarks shows that our proposed solution significantly improves the performance of CZSL, and its components have been verified by solid ablation studies.
Recent advancements in pre-trained Vision-Language Models (VLMs) have highlighted the significant potential of prompt tuning for adapting these models to a wide range of downstream tasks. However, existing prompt tuning methods typically map an image to a single representation, limiting the model's ability to capture the diverse ways an image can be described. To address this limitation, we investigate the impact of visual prompts on the model's generalization capability and introduce a novel method termed Multi-Representation Guided Prompt Tuning (MePT). Specifically, MePT employs a three-branch framework that focuses on diverse salient regions, uncovering the inherent knowledge within images which is crucial for robust generalization. Further, we employ efficient self-ensemble techniques to integrate these versatile image representations, allowing MePT to learn all conditional, marginal, and fine-grained distributions effectively. We validate the effectiveness of MePT through extensive experiments, demonstrating significant improvements on both base-to-novel class prediction and domain generalization tasks.
Vision-based motion estimation methods show promise in accurately and unobtrusively estimating human body motion for healthcare purposes. However, these methods are not specifically designed for healthcare purposes and face challenges in real-world applications. Human pose estimation methods often lack the accuracy needed for detecting fine-grained, subtle body movements, while optical flow-based methods struggle with poor lighting conditions and unseen real-world data. These issues result in human body motion estimation errors, particularly during critical medical situations where the body is motionless, such as during unconsciousness. To address these challenges and improve the accuracy of human body motion estimation for healthcare purposes, we propose the OPPH operator designed to enhance current vision-based motion estimation methods. This operator, which considers human body movement and noise properties, functions as a multi-stage filter. Results tested on two real-world and one synthetic human motion dataset demonstrate that the operator effectively removes real-world noise, significantly enhances the detection of motionless states, maintains the accuracy of estimating active body movements, and maintains long-term body movement trends. This method could be beneficial for analyzing both critical medical events and chronic medical conditions.
Explainable Recommendation task is designed to receive a pair of user and item and output explanations to justify why an item is recommended to a user. Many models treat review-generation as a proxy of explainable recommendation. Although they are able to generate fluent and grammatical sentences, they suffer from generality and hallucination issues. We propose a personalized, aspect-controlled model called Multi-Aspect Prompt LEarner (MAPLE), in which it integrates aspect category as another input dimension to facilitate the memorization of fine-grained aspect terms. Experiments on two real-world review datasets in restaurant domain show that MAPLE outperforms the baseline review-generation models in terms of text and feature diversity while maintaining excellent coherence and factual relevance. We further treat MAPLE as a retriever component in the retriever-reader framework and employ a Large-Language Model (LLM) as the reader, showing that MAPLE's explanation along with the LLM's comprehension ability leads to enriched and personalized explanation as a result. We will release the code and data in this http upon acceptance.
Large Language Models (LLMs) have reshaped the landscape of artificial intelligence by demonstrating exceptional performance across various tasks. However, substantial computational requirements make their deployment challenging on devices with limited resources. Recently, compression methods using low-rank matrix techniques have shown promise, yet these often lead to degraded accuracy or introduce significant overhead in parameters and inference latency. This paper introduces \textbf{Mo}dular \textbf{De}composition (MoDeGPT), a novel structured compression framework that does not need recovery fine-tuning while resolving the above drawbacks. MoDeGPT partitions the Transformer block into modules comprised of matrix pairs and reduces the hidden dimensions via reconstructing the module-level outputs. MoDeGPT is developed based on a theoretical framework that utilizes three well-established matrix decomposition algorithms -- Nystr\"om approximation, CR decomposition, and SVD -- and applies them to our redefined transformer modules. Our comprehensive experiments show MoDeGPT, without backward propagation, matches or surpasses previous structured compression methods that rely on gradient information, and saves 98% of compute costs on compressing a 13B model. On \textsc{Llama}-2/3 and OPT models, MoDeGPT maintains 90-95% zero-shot performance with 25-30% compression rates. Moreover, the compression can be done on a single GPU within a few hours and increases the inference throughput by up to 46%.
We propose a new high dimensional semiparametric principal component analysis (PCA) method, named Copula Component Analysis (COCA). The semiparametric model assumes that, after unspecified marginally monotone transformations, the distributions are multivariate Gaussian. COCA improves upon PCA and sparse PCA in three aspects: (i) It is robust to modeling assumptions; (ii) It is robust to outliers and data contamination; (iii) It is scale-invariant and yields more interpretable results. We prove that the COCA estimators obtain fast estimation rates and are feature selection consistent when the dimension is nearly exponentially large relative to the sample size. Careful experiments confirm that COCA outperforms sparse PCA on both synthetic and real-world datasets.